Our math model found tradeoffs in MPOX vaccination strategies and supports smaller doses to protect a larger population at risk When there is a shortage of vaccine available in a public health crisis, one policy option is to offer the full dose to a small population or alternatively offer a smaller dose to a larger…
Category: Models
Fall 2020 Scientific Speaking
Effective scientific communication is really hard This summer I met a few cast members from Saturday Night Live, including the comedian Mikey Day. I’m a big fan of the show and have watched it since old enough to stay up until 11:35pm on Saturdays. We talked about the their creative solutions for comedy during lock…
Lessons from Cost-Effectiveness of HIV vaccines for COVID Vaccines
Will HIV vaccines compete with existing HIV prevention strategies? Who is doing COVID vaccine cost-effectiveness analysis? Fred Hutch Science Spotlight translated the math in our peer-reviewed paper published in the Journal of the International AIDS Society to explain the economic tradeoffs of delivering an HIV vaccine in Seattle in the future. Our prior review of…
Solid Machine Learning Model Predicts New HIV Cases Using EHR Data
Incredible new research from Harvard and Kaiser contributed two substantial leaps forward this summer: first in the useful application of machine learning predictions using electronic health records and second in the accurate targeting of people who can benefit the most from HIV pre-exposure prophylaxis. This paper in Lancet HIV by Marcus and colleagues is so good…
How to find acute HIV cases in a hot epidemic
One of the most highly infectious time periods in the life of a person with HIV is also when that person is most likely unaware of their HIV status. This is the acute stage. Shortly after infection, the virus explodes with a measurable peak in the number of copies floating around. This feature of the…
ACA Medicaid expansion eliminated racial disparities in timely cancer treatment
A summary about press coverage of results from a research study from Flatiron Health and Yale, presented at the ASCO 2019 Plenary Session. We learned that Affordable Care Act (ACA) Medicaid expansion was associated with reduction in racial disparity in timely treatment of advanced cancer. Results were reported in the The Washington Post, Wall Street…
Causal Inference Book Club
Want to join our book club? We’re reading the new Causal Inference Book by Miguel Hernan and James Robins. The book is forthcoming publication by Chapman & Hall/CRC and it is available for FREE right now to download from Harvard. Every few weeks my colleagues and I meet up to discuss a few chapters. We…
Should we pay some people to take their HIV drugs?
There is little prior evidence of effective interventions to improve viral suppression, despite this being a critical step in the HIV care continuum as described in the National HIV/AIDS Strategy for the United States.
Economic Impact of Comparative-Effectiveness Studies
@AcademyHealth #ARM2018 attendees: join me on Monday at 3:15 pm in room 605-606, where Anirban Basu will present our work in collaboration with the Patient Centered Outcomes Research Institute (PCORI) to quantify the potential economic impact of the findings from comparative-effectiveness research studies. Goal Our goal was to understand the potential benefits of implementing comparative-effectiveness…
BBC Interview
On Tuesday, April 17, the journal Nature Scientific Reports published our paper “Projected effectiveness and added value of HIV vaccination campaigns in South Africa: A modeling study.” A few hours later, a reporter from BBC World Service reached out to discuss the the results of our study. Live Interview You can listen to this clip with…